產品屬性：
產品名稱 | EDANS |
規格 | 10mM*1 mL in DMSO、100 mg |
貨號 | EY-01Y19768 |
Cas No.: 50402-56-7
別名: N/A
化學名: N/A
分子式: C12H14N2O3S
分子量: 266.32
溶解度: DMSO: 13.89 mg/mL (52.16 mM)
儲存條件: 4°C, protect from light, stored under nitrogen
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1].The peptide sequence of EDANS is derived from a natural processing site for HIV-1 PR[1].Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that was linearly related to the extent of substrate hydrolysis[1].[1]. E D Matayoshi, et al. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science. 1990 Feb 23;247(4945):954-8.
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