產品屬性：
產品名稱 | Taurolithocholic Acid (sodium salt) |
規格 | 5mg、10mg、50mg |
貨號 | EY-01Y16081 |
Cas No.: 6042-32-6
別名: N/A
化學名: N/A
分子式: C26H44NO5S?Na
分子量: 505.7
溶解度: DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 1 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Taurolithocholic acid (TLCA) is a taurine-conjugated form of the secondary bile acid lithocholic acid . TLCA (75 μM) increases caspase-3 and -7 activity in Hep3B cells transfected with sodium taurocholate cotransporting peptide (NTCP), but not nontransfected Hep3B cells. It has been used to induce cholestasis in ex vivo and in vivo animal models of hepatocellular cholestasis. Serum levels of TLCA increase approximately 5-fold in within two hours during an oral lipid tolerance test in humans.
特別提醒公司產品僅供科研使用
