產(chǎn)品屬性：
產(chǎn)品名稱(chēng) | SBI-477 |
規(guī)格 | 10mM*1mL in DMSO、1mg、5mg、10mg、50mg、100mg |
貨號(hào) | EY-01Y15180 |
Cas No.: 781628-99-7
別名: N/A
化學(xué)名: N/A
分子式: C24H25N3O6S
分子量: 483.54
溶解度: DMSO: 65 mg/mL (134.43 mM)
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes[1].[1]. Ahn B, et al. MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling. J Clin Invest. 2016 Sep 1;126(9):3567-79.
特別提醒公司產(chǎn)品僅供科研使用
