產(chǎn)品屬性：
產(chǎn)品名稱 | RGX-104 free Acid |
規(guī)格 | 10mM*1mL in DMSO、2mg、5mg、10mg、25mg、50mg、100mg、200mg500mg、 |
貨號(hào) | EY-01Y14044 |
Cas No.: 610318-54-2
別名: N/A
化學(xué)名: N/A
分子式: C34H33ClF3NO3
分子量: 596.08
溶解度: DMSO: ≥ 130 mg/mL (218.09 mM); H2O: < 0.1 mg/mL (insoluble)
儲(chǔ)存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
RGX-104 free Acid is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene.LXR[1]Oral administration of RGX-104 (100 mg/kg, daily) to animals bearing palpable tumors significantly suppresses the growth of multiple cancer types. Co-administration of RGX-104 with anti-PD-1 is superior to administration of either RGX-104 or anti-PD-1 alone. Importantly, co-administration of RGX-104 with anti-PD-1 therapy is well tolerated by mice, with no overt signs of toxicity[1].
特別提醒公司產(chǎn)品僅供科研使用
