產(chǎn)品屬性：

Cas No.: 56563-17-8

別名: N/A

化學名: N/A

分子式: C11H8FN3O3

分子量: 249.2

溶解度: DMSO: 5 mg/mL (20.06 mM)

儲存條件: 4°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.

Shipping ConditionEvaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

PluriSIn #2 is a selective transcriptional inhibitor of topoisomerase II α (TOP2A). PluriSIn #2 is a compound that selectively eliminates undifferentiated human pluripotent stem cells (hPSCs)[1].PluriSIn #2 (20 μM; 12 hours) treatment reduces TOP2A expression at the protein level[1].A 24h exposure of PluriSIn #2 (20 μM) is sufficient to induce massive cell death in hPSCs, but doesn't affect the viability of various other cell types derived from them[1].Western Blot Analysis[1]    Cell Line:B153 and HUES9 human pluripotent stem cells (hPSCs)[1]. Uri Ben-David, et al. Brief reports: Controlling the survival of human pluripotent stem cells by small molecule-based targeting of topoisomerase II alpha. Stem Cells. 2015 Mar;33(3):1013-9.
特別提醒公司產(chǎn)品僅供科研使用