產品屬性：
產品名稱 | Rp-8-CPT-Cyclic AMP (sodium salt) |
規(guī)格 | 500μg、1mg |
貨號 | EY-01Y12729 |
Cas No.: 221905-35-7
別名: N/A
化學名: 8-[(4-chlorophenyl)thio]-adenosine cyclic 3',5'-[hydrogen (R)-phosphorothioate], monosodium salt
分子式: C16H14ClN5O5PS2?Na
分子量: 509.8
溶解度: 25mg/mL in DMSO, 30mg/mL in DMF, 0.5mg/mL in Ethanol
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Rp-8-CPT-cAMP is a structural combination of the lipophilic and non-hydrolyzable cAMP analogs, 8-CPT-cyclic AMP and Rp-cyclic AMPS .[1] It functions as a site-selective inhibitor of protein kinase A (PKA) type I and II, with preference towards site A of type I and site B of type II.2 By occupying cAMP binding sites at the regulatory subunit of PKA, Rp-8-CPT-cAMP prevents the kinase holoenzyme from dissociative activation.[2],[3]
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