產(chǎn)品屬性：
產(chǎn)品名稱 | Tomatidine (hydrochloride) |
規(guī)格 | 10mg、25mg、50mg、100mg |
貨號(hào) | EY-01Y10366 |
Cas No.: 6192-62-7
別名: N/A
化學(xué)名: N/A
分子式: C27H45NO2?HCl
分子量: 452.1
溶解度: Methanol: 10 mg/ml
儲(chǔ)存條件: 4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Tomatidine is a steroidal alkaloid that has been found in the skins and leaves of tomatoes. It suppresses NF-κB signaling in LPS-stimulated macrophages, blocking induced expression of inducible nitric oxide synthase (iNOS) and COX-2. Tomatidine inhibits acid sphingomyelinase activity by 84.2% when used at a concentration of 10 mM. It also has antibacterial properties, preferentially blocking the replication of S. aureus variants that are pathogenic in cystic fibrosis over normal strains (MICs = 0.12 and >16 μg/ml, respectively). It prevents skeletal muscle atrophy associated with fasting or spinal cord injury in mice. Tomatidine has also been used as a negative control for cyclopamine in studies involving signaling mediated by the hedgehog pathway.
特別提醒公司產(chǎn)品僅供科研使用
